TEAM ENCALADA

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Sandra E Encalada, PhD

Principal Investigator
Arlene and Arnold Goldstein Associate Professor
encalada [at] scripps [dot] edu

Sandra is an Associate Professor in the Department of Molecular Medicine and an Investigator of the Dorris Neuroscience Center, and of the Neurodegeneration New Medicines Center at Scripps Research. She received her International Baccalaureate (I.B.) degree from the United World College - USA, and her B. A. from Earlham College in Physics with a minor in Biology. Sandra obtained her PhD in Molecular Genetics from the University of Oregon, where she studied under the mentorship of Bruce Bowerman. She was a Damon Runyon Postdoctoral Fellow at UC San Diego in the laboratory or Larry S. B. Goldstein where she characterized the mechanisms of transport of the prion protein. She is the recipient of The Glenn Foundation Award for Research in Biological Mechanisms of Aging, The Baxter Foundation Young Faculty Award, and The Ellison Medical Foundation New Scholar in Aging Award. Outside of the lab, she enjoys swimming in the ocean, playing the piano, and picking bugs with her daughter.

Yin Wu

Graduate Student
yinwu [at] scripps [dot] edu


Yin is a graduate student in the Scripps Doctoral Program in Chemical and Biological Sciences. She completed her B.S. in Life Sciences at University of Science and Technology of China in the Special Class for the Gifted Young. For her Ph.D. research, she works in the lab of Sandra Encalada to study the mechanisms of tau aggregation in axons of mammalian neurons. In her spare time, she likes doing exercise, reading suspense novels and doing sudoku (the failure of which often results in tears).

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Kiley Hughes-Wiles, PhD

Postdoctoral Associate
kihughes [at] scripps [dot] edu


Kiley is a postdoctoral fellow under the NIH-NIAAA T32 training grant. She received her B.S. in Biochemistry and Behavioral Neuroscience at Western Washington University in 2017, and her PhD in Biological Sciences from Illinois State University in 2022 where she worked in the lab of Andrés Vidal-Gadea to understand the pathogenesis of Duchenne muscular dystrophy in C. elegans. Her postdoctoral work focuses on understanding the cellular consequences of mutant prion protein aggregation in mammalian axons. When not in the lab, Kiley enjoys spending time with her friends and family, playing with her cats, listening to audiobooks, and exploring the outdoors.

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Anna L. Tran-Crie
Administrative Assistant (the best!)
Email: annacrie [at] scripps [dot] edu

Tai Chaiamarit

Graduate Student
taich [at] scripps [dot] edu

Tai is a joint graduate student between Scripps Research and Oxford University in England under the Skaggs-Oxford program. Tai received a B.S. in Biology with Neurobiology from University of Wisconsin-Madison in 2017. Tai joined the Encalada Lab from 2018-2020 to work on elucidating the mechanism of how mutant prion protein aggregates are formed and how they disrupt neuronal function. Tai is currently working in Ilan Davis lab in the Biochemistry department at Oxford on the mechanism and function of RNA localization in membrane trafficking during new synapse formation. Tai's hobbies outside of the lab are hiking, traveling, and cooking.

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Subhalakshmi Guha, PhD
Postdoctoral Fellow
sguha [at] scripps [dot] edu

Subhalakshmi is a post-doctoral fellow, under the CTW Foundation Fellowship grant. She received her B.S. in Microbiology and M.S. in Biochemistry. She completed her Ph.D. in 2022 from Indian Institute of Chemical Biology under the guidance of Prof. Subhas C. Biswas focusing primarily on how astrocytes protect neuron in the early phases of Alzheimer’s Disease. Currently she is interested in understanding how faulty neuroaxonal trafficking leads to pathological and phenotypic impairment in mouse brain models of prion disease and in tauopathy mouse models. When not in lab, Subhalakshmi enjoys traveling with her spouse, trying out new cuisines, listening to music, swimming and sky-gazing.

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Baby Yoda
Upcoming Graduate Student and Grand Master
Email: yoda [at] coruscant [dot] edu

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Keishla Sanchez Ortiz

Graduate Student
ksanchez [at] scripps [dot] edu


Keishla is a second-year graduate student and a Dorris Neuroscience Scholar from Jayuya, Puerto Rico. She received her B.S. in Industrial Biotechnology with minors in Biochemistry and Bioprocess Engineering from the University of Puerto Rico- Mayagüez. During her undergraduate career, she was part of Dr. Juan López Garriga’s laboratory studying the interactions of endogenously produced hydrogen sulfide with hemoglobin and myoglobin. She also worked as a co-op technician at Abbvie Biotechnology, Ltd where she oversaw the manufacturing process of biological drugs Humira and Skyrizi. After obtaining her B.S. in 2020, she worked at CDI Laboratories in Mayagüez, Puerto Rico producing ultra-specific monoclonal antibodies and participating in the approval of Sentry-Ag, an antigen-based rapid test for SARS-CoV-2 detection. Her graduate work focuses on characterizing the links between viral-driven neuronal fusion and neurodegeneration. Outside of the lab, Keishla enjoys going to the beach and the theater, cooking, baking, sewing clothes and watching true crime documentaries.

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Kiera Fleck
Rotating Graduate Student
kfleck [at] scripps [dot] edu


Kiera is a first-year graduate student currently rotating in Dr. Encalada’s lab. She received her B.S.E in biomedical engineering and a minor in mathematics from Arizona State University in May 2022. As an undergraduate research aide, she investigated the use of genetically modified Salmonella as a pH-modulator to explore and manipulate the tumor microenvironment. In her free time, Kiera enjoys playing the piano, baking, and visiting the beach. 

ALUMNI

Graduate Students:
George Campbell, PhD - Sr. Researcher at St. Jude Children's Research Hospital
Miguel Alves Ferreira - Ph.D. Student at University of Porto

Postdoctoral Fellows:
Adriaan Verhelle, PhD 
Andre Leitao, PhD 
Nandini Shukla, PhD 
Adeola Adeyoma, PhD
David Soriano Castell, PhD - Postdoc Salk Institute
Romain Chassefeyre, PhD - Scientist at Evotec, France
Sylvia Neumann, PhD - Project Scientist and Lab Manager, UCLA
Erin Greiner, PhD - Territory Account Manager, Illumina, San Diego


Assistants:
Nirvan Rouzbeh
Diana Gonzales
Jesse Holt
Andrew Huang
Cynthia Cho
Leena McCann

Rotation Students:

Cristian Wulkop-Gil

Julia Jones

Chung Chih Liu 

Lara Ibrahim

Amanda Sul

Ana Verduzca

Hao Wang

Belle Noxon

Whitney Baldridge

Carlos Aguirre

Cong Ba Dinht  

Paulo Onuchic
Cecilia Monteiro 
Rigo Cintron-Colon
Alyson Smith
Eveline Lee
Jennifer Kefauver
Linxuan Yan 
Han-Hsuan Liu

Melody Campbell

Undergraduate Students: 

Desi Martin

Phil Frankino

Krystal Lawrence