Encalada Lab Publications

A more complete list of our published work can be found at PubMed:

Butler VJ, Salazar DA, Soriano-Castell D, Alves-Ferreira M, Dennissen FJA, Vohra M, Oses-Prieto JA, Li KH, Wang AL, Jing B, Li B, Groisman A, Gutierrez E, Mooney S, Burlingame AL, Ashrafi, K, Mandelkow E-M, Encalada SE, Kao AW.  Tau/MAPT disease-associated variant A152T alters tau function and toxicity via impaired retrograde axonal transport. Human Molecular Genetics. 2018 Dec. 26. doi: 10.1093/hmg/ddy442. [Epub ahead of print]. PMID: 30590647. 

[PubMed Link]

Madhivanan K, Greiner ER, Alves-Ferreira M, Soriano-Castell D, Rouzbeh N, Aguirre CA, Paulsson JF, Chapman J, Jian X, Ooi FK, Lemos C, Dillin A, Prahlad V, Kelly JW, Encalada SE. Cellular Clearance of Circulating Transthyretin Decreases Cell Non-Autonomous Proteotoxicity in Caenorhabditis elegans.  Proc Natl Acad Sci U S A. 2018 Jul 30. pii: 201801117. doi: 10.1073/pnas.1801117115. [Epub ahead of print]. PMID:30061394.

[PubMed Link]

Neumann S, Chassefeyre R, Campbell GE, Encalada SE. KymoAnalyzer: a software tool for the quantitative analysis of intracellular transport in neurons. Traffic, 2017 Jan;18(1):71-88. doi: 10.1111/tra.12456. Epub 2016 Dec 11.

[PubMed Link]

Click here to download the KymoAnalyzer software!


Rangaraju, S., Solis G.M., Thompson R.C., Gomez-Amaro R.L., Kurian L., Encalada S.E., Niculescu III, A.B., Salomon D.R., Petrascheck M. Suppression of transcriptional drift extends C. elegans lifespan by postponing the onset of mortality. eLife 2015 Dec 1;4:e08833. doi: 10.7554/eLife.08833.

[PubMed Link]


Eisele Y.S., Monteiro C., Fearns C., Encalada S.E., Wiseman R.L., Powers E.T., Kelly J.W. Targeting protein aggregation for the treatment of degenerative diseases. Nat Rev Drug Discov. 2015 Nov;14(11):759-80. doi: 10.1038/nrd4593. Epub 2015 Sep 4. [PubMed Link]


Baranczak A., Liu Y., Connelly S., Dan D.U., W-E, Greiner E.R., Genereux J.C., Wiseman R.L., Eisele Y.S., Bradbury N.C., Dong J., Noodleman L., Sharpless K.B., Wilson I.A., Encalada S.E.*, Kelly J.W.* A fluorogenic aryl fluorosulfate for intraorganellar transthyretin imaging in living cells and in Caenorhabditis elegans. J Am Chem Soc. 2015 Jun 17;137(23):7404-14. doi: 10.1021/jacs.5b03042. Epub 2015 Jun 8. [PubMed Link]
*Co-corresponding Authors


Neumann S., Campbell G.E., Szpankowski L., Goldstein L.S.B., Encalada S.E.* Characterizing the composition of molecular motors on moving axonal cargo using “Cargo Mapping” analysis. J Vis Exp. 2014 Oct 30;(92):e52029. doi: 10.3791/52029. [PubMed Link]
*Corresponding Author
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Encalada S.E.*, & Goldstein L.S.B.* Biophysical challenges to axonal transport: motor-cargo deficiencies and neurodegeneration. Annu Rev Biophys. 2014;43:141-69. doi: 10.1146/annurev-biophys-051013-022746. [PubMed Link]

*Co-Corresponding authors


Otero M.G., Alloatti M., Cromberg L.E., Almenar-Queralt A., Encalada S.E., Pozo Devoto V.M., Bruno L., Goldstein L.S.B., Falzone T.L. Fast axonal transport of the proteasome complex depends on membrane interaction and molecular motor function. J Cell Sci. 2014 Apr 1;127(Pt 7):1537-49. doi: 10.1242/jcs.140780. Epub 2014 Feb 12. [PubMed Link]


Szpankowski L., Encalada S.E., Goldstein L.S.B. Subpixel colocalization reveals amyloid precursor protein-dependent kinesin-1 and dynein association with axonal vesicles. Proc Natl Acad Sci U S A. 2012 May 29;109(22):8582-7. doi: 10.1073/pnas.1120510109. Epub 2012 May 11. [PubMed Link]
          Cited in Faculty of 1000:
              Stevens, D:



Encalada S.E., Szpankowski L., Xia C.H., Goldstein L.S.B. Stable kinesin and dynein assemblies drive the axonal transport of mammalian prion protein vesicles. Cell. 2011 Feb 18;144(4):551-65. doi: 10.1016/j.cell.2011.01.021. [PubMed Link]

          Cited in Faculty of 1000:
              Sheng Z:
              Kuta A, Fisher E: http://f1000.com/prime/8671969
          Cited in Alzheimer Research Forum:



Encalada S.E., Goldstein L.S.B. Axonal Transport of the Prion Protein and Prion Neuroinvasion. The New Encyclopedia of Neuroscience (Larry Squire, ed.). 2009. Elsevier, Oxford, UK, pp. 1071-1075.



Encalada S.E., Moya K.L., Lehmann S., Zahn R. The role of the prion protein in the molecular basis for synaptic plasticity and nervous system development. J Mol Neurosci. 2008;34(1):9-15. Epub 2007 Jun 14. [PubMed Link]



Encalada S.E., Willis J., Lyczak R., Bowerman B. A spindle checkpoint functions during mitosis in the early Caenorhabditis elegans embryo. Mol Biol Cell. 2005 Mar;16(3):1056-70. Epub 2004 Dec 22. (cover). [PubMed Link]



Gomes J.E., Encalada S.E., Swan K.A., Shelton C.A., Carter J.C., Bowerman B. The maternal gene spn-4 encodes a predicted RRM protein required for mitotic spindle orientation and cell fate patterning in early Caenorhabditis elegans embryos. Development. 2001 Nov;128(21):4301-14. [PubMed Link]



Encalada S.E., Martin P.R., Phillips J.B., Lyczak R., Hamill D.R., Swan K.A., Bowerman B. DNA replication defects delay cell division and disrupt cell polarity in early Caenorhabditis elegans embryos.  Dev Biol. 2000 Dec 15;228(2):225-38.. [PubMed Link]



Fernando P., Pfrender M.E., Encalada S.E., Lande R. Mitochondrial DNA variation, phylogeography and population structure of the Asian elephant. Heredity (Edinb). 2000 Mar;84 ( Pt 3):362-72. [PubMed Link]



Encalada S.E., Zurita J.C., Bowen B.W. Genetic consequences of coastal development:  the sea turtle rookeries at X’cacel Mexico. Marine Turtle Newsletter, 1999 83:8-10. [Link]



Bolten A.B., Bjorndal K.A., Martins H.R., Dellinger T., Biscoito M.J., Encalada S.E., Bowen B.W. Transatlantic developmental migrations of loggerhead sea turtles demonstrated by mtDNA sequence analysis.  Ecological Applications 1998 8:1-7. [Link]



Encalada S.E., Bjorndal K.A., Bolten A.B., Zurita J.C., Schroeder B., Possardt, E., Sears C.J., Bowen B.W. (1998). Population structure of loggerhead turtle (Caretta caretta) nesting colonies in the Atlantic and Mediterranean as inferred from mitochondrial DNA control region sequences. Marine Biology 1998 130:567-575. [Link]



Lahanas P.N., Bjorndal K.A,. Bolten A.B., Encalada S.E., Miyamoto M.M., Valverde R.A., Bowen B.W. Genetic composition of a green turtle (Chelonia mydas) feeding ground population:  evidence for multiple origins.  Marine Biology 1998 130:345-352. [Link]



Rankin-Baransky K., Williams C.J., Bowen B.W., Encalada S.E., Spotila J.R. Origin of loggerhead sea turtles in the western north Atlantic as determined by mtDNA analysis. In: Proceedings of the Seventeenth Annual Sea Turtle Symposium. (Epperly, S. P., and Braun, J. Compilers), U.S. Dep.  Commer.  NOAA Tech Memo. 1998 NMFS-SEFSC-415. 294 pp.; 1998, p. 79.



Encalada S.E, Lahanas P.N., Bjorndal K.A., Bolten A.B., Miyamoto M.M., Bowen B.W. Phylogeography and population structure of the green turtle (Chelonia mydas) in the Atlantic Ocean and Mediterranean Sea:  a mitochondrial DNA control region assessment.  Mol Ecol. 1996 Aug;5(4):473-83. [PubMed Link]



Encalada S.E. Conservation genetics of Atlantic green turtles:  cases of imminent rookery extinctions.  In:  Proceedings of the First Sea Turtle Genetics Symposium (Bowen, B. W., and W. N. Witzell, eds). NOAA Technical Memorandum 1996 NMFS-SEFSC-396, pp33-40.



Abreu-Grobois F.A., Bass A.L., Dutton P.H., Encalada S.E. PCR-RFLP analysis of sea turtle populations in the era of DNA sequencing:  is it still useful? In:  Proceedings of the First Sea Turtle Genetics Symposium (Bowen, B. W., and W. N. Witzell, eds).  NOAA Technical Memorandum 1996 NMFS-SEFSC-396, pp55-67.



Encalada S.E., Eckert S.A., Bowen B.W. Forensic applications of mitochondrial DNA markers:  origin of a confiscated green turtle.  Marine Turtle Newsletter 1994 66:1-3. [Link]